Quinoline, 4-chloro-7-(phenylmethoxy)-

Quinoline, 4-chloro-7-(phenylmethoxy)- - Names and Identifiers

Name	7-BENZYLOXY-4-CHLOROQUINOLINE
Synonyms	102579 4-chloro-7-(phenylMethoxy 4-chloro-7-benzoxyquinoline 4-chloro-7-phenoxy-quinoline 7-BENZYLOXY-4-CHLOROQUINOLINE 4-chloro-7-phenylmethoxyquinoline Quinoline, 4-chloro-7-(phenylmethoxy)-
CAS	178984-56-0
InChI	InChI=1/C16H12ClNO/c17-15-8-9-18-16-10-13(6-7-14(15)16)19-11-12-4-2-1-3-5-12/h1-10H,11H2

Quinoline, 4-chloro-7-(phenylmethoxy)- - Physico-chemical Properties

Molecular Formula	C16H12ClNO
Molar Mass	269.73
Density	1.263±0.06 g/cm3(Predicted)
Boling Point	414.1±30.0 °C(Predicted)
Flash Point	204.215°C
Vapor Presure	0mmHg at 25°C
pKa	3.86±0.27(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.654

Quinoline, 4-chloro-7-(phenylmethoxy)- - Introduction

Also known as BCQ, it is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: BCQ appears as a white crystalline solid.
-Solubility: BCQ dissolves in most organic solvents, such as alcohols, ethers and chlorinated hydrocarbons. Its solubility in water is relatively low.
-Melting point: The melting point of BCQ is about 160-162 degrees Celsius.

Use:
-Treatment of malaria: BCQ is widely used to treat malaria, especially in newborns and pregnant women.
-Antiviral effect: Studies have shown that BCQ has an inhibitory effect on some viruses such as hepatitis B virus and dengue virus in vitro, but its clinical use has not been clarified.

Method:
-A commonly used method for preparing BCQ is obtained by reacting 4-chloroquinoline with benzyl alcohol. A certain catalyst and solvent are used in the reaction process.

Safety Information:
-A small amount of BCQ may cause skin allergic reactions, so you need to pay attention to personal protection when exposed.
-It may cause eye and respiratory irritation in some people, so use it to avoid inhalation or eye contact.
-The toxicity and carcinogenicity of BCQ are not fully studied, so it is necessary to pay attention to safety when using and disposing, and operate in accordance with relevant safe operating procedures.

Last Update：2024-04-09 20:44:15